ChatGPT Prompts for Doctors: 10 Clinical AI Templates

ChatGPT Prompts for Doctors: 10 Clinical AI Templates

@Sarah Mitchell
May 7, 2026
9 min
#chatgpt for doctors#medical ai prompts#clinical documentation ai#doctor chatgpt#healthcare ai#medical prompts
$ cat article.md | head -n 3
10 practical ChatGPT prompts for physicians — clinical documentation, patient education, differential diagnosis frameworks, and medical communication templates.

The integration of AI into clinical medicine is accelerating. Physicians are using ChatGPT and similar models for documentation assistance, patient education material creation, clinical reasoning support, and administrative efficiency. The key is using these tools appropriately — as thinking and writing aids, never as diagnostic replacements — and with proper attention to patient privacy.

Critical disclaimer: These prompts are for physician use as thinking and writing aids only. AI cannot diagnose patients. Always apply clinical judgment. Never share identifying patient information with AI systems.

Where AI Genuinely Helps in Clinical Practice

The highest-value applications for physician AI use are:

  1. Patient communication materials: Translating complex medical information into accessible language
  2. Documentation drafting: Initial SOAP note structure, discharge summary frameworks
  3. Differential diagnosis brainstorming: Ensuring completeness, not replacing clinical judgment
  4. Medical education: Explaining concepts, creating case-based teaching materials
  5. Administrative efficiency: Prior authorization language, referral letters, literature review

10 Clinical AI Prompt Templates

1. Patient Education Material — Plain Language

prompt
Create patient education material explaining [medical condition/procedure/
medication] for a patient with approximately an 8th-grade reading level.

Include:
- What this is (simple explanation)
- Why it matters for their health
- What they need to know about [treatment/medication/procedure]
- Common questions and answers (3-5 FAQs)
- When to call the doctor (specific warning signs)
- What to expect (timeline, sensations, recovery if applicable)

Use: Short sentences, plain language, no medical jargon (or define any
medical term immediately when used), second person ("you will...").
Avoid: Jargon, complex sentences, percentages without context, medical
abbreviations.
Length: Readable in 3-5 minutes.

2. Differential Diagnosis Framework

prompt
You are helping a physician think through a differential diagnosis (not making a
diagnosis — this is a structured brainstorming exercise).

Chief complaint: [symptoms and presentation]
Patient demographics: [age, relevant demographics — no identifying information]
Relevant history: [pertinent positives and negatives]
Available findings: [vital signs, exam findings, available lab/imaging — no patient identifiers]

Generate a structured differential using the VINDICATE framework:
V - Vascular
I - Infectious/Inflammatory
N - Neoplastic
D - Degenerative/Drugs
I - Idiopathic/Iatrogenic
C - Congenital
A - Autoimmune/Allergic
T - Traumatic
E - Endocrine/Metabolic

For each applicable category: List 2-3 conditions to consider.
Note: "Must not miss" diagnoses should be flagged prominently.
This is a thinking tool only — clinical judgment and examination are essential.

3. SOAP Note Structure (Documentation Assistance)

prompt
Create a structured SOAP note template for the following clinical scenario:

Visit type: [new patient/follow-up/urgent/consult]
Chief complaint: [complaint — no patient identifiers]
Clinical summary: [key history and exam findings — de-identified]

Generate a complete SOAP note structure with:
S (Subjective): Organized chief complaint, HPI, relevant ROS, PMH/PSH/FH/SH framework
O (Objective): Vital signs, physical exam by system
A (Assessment): Diagnosis/diagnoses with supporting rationale
P (Plan): Problem-by-problem plan with medications, referrals, follow-up

Use standard medical documentation format.
Mark where physician must fill in specific findings with [PHYSICIAN INPUT NEEDED].
This is a drafting tool — physician must review, edit, and verify all content.

4. Prior Authorization Letter

prompt
Draft a prior authorization letter for the following:

Medication/Procedure: [name]
Clinical indication: [diagnosis and rationale — no patient identifiers]
Why alternatives are not appropriate: [medical necessity argument]
Relevant clinical guidelines: [if known — I'll verify/add specific citations]

Format as a professional prior authorization letter including:
- Medical necessity statement
- Clinical documentation summary
- Failure of or contraindication to alternatives (if applicable)
- Relevant clinical evidence for this treatment
- Request for specific authorization

Write in authoritative clinical language. Mark where specific patient data
and signatures must be added with [PHYSICIAN COMPLETES].

5. Medical Referral Letter

prompt
Create a medical referral letter template for referring a patient to [specialty]:

Reason for referral: [clinical question or concern — de-identified]
Relevant clinical background: [pertinent history and findings — de-identified]
Specific question for consultant: [what you need the specialist to address]
Urgency: [routine/semi-urgent/urgent]
What has been done so far: [relevant workup, treatments tried]

Format as a professional referral letter with:
- Clear reason for referral in first paragraph
- Pertinent clinical history
- Specific consultation questions
- Urgency clearly stated
- Contact information placeholder

Tone: Collegial, professional, respecting the consultant's expertise while
providing all information needed for them to prepare.

6. Case Presentation Template

prompt
Structure a case presentation for [educational conference/grand rounds/M&M/
board exam practice] using the following clinical scenario:

Case summary: [de-identified clinical scenario]
Conference type: [grand rounds/M&M/clinical case conference/board review]
Teaching objectives: [what should participants learn from this case]

Structure the presentation with:
1. Chief complaint and HPI (presented as narrative)
2. Physical examination findings
3. Initial workup and findings
4. Differential diagnosis with discussion
5. Diagnostic approach chosen and rationale
6. Final diagnosis (or learning point if diagnostic uncertainty)
7. Management and outcome
8. Key teaching points (3-5 bullet points)
9. Discussion questions for attendees (3-4 questions)

Format for verbal presentation, appropriate for [audience level — medical
students/residents/faculty].

7. Patient Question Response — Written Communication

prompt
Draft a written response to a patient question for the patient portal/after-visit
summary, maintaining appropriate clinical caution and warmth:

Question topic: [general topic — no patient identifiers]
Clinical context: [relevant background — de-identified]
Core message to communicate: [what needs to be conveyed]
Action needed from patient: [if any]

Write a response that:
- Directly addresses the question in plain language
- Is appropriately reassuring without overpromising
- Includes necessary caveats about seeking care if symptoms worsen
- Provides clear next steps
- Is warm and human, not bureaucratic

Length: 150-250 words — substantive but not overwhelming.
Include: Appropriate closing directing patient to call if concerns worsen.
Physician must review before sending — mark any areas needing clinical
verification with [VERIFY].

8. Medication Counseling Points

prompt
Generate medication counseling talking points for discussing [medication] with
a patient starting this treatment.

Include:
1. What this medication does (one sentence in plain language)
2. How to take it (dosing, timing, with/without food)
3. Most common side effects (top 3-5) and what to do about them
4. Serious side effects requiring immediate care
5. Drug interactions to watch for (common ones)
6. What to do if a dose is missed
7. How long before they might notice benefits
8. Monitoring needed (labs, follow-up)
9. Cost/adherence resources if commonly expensive

Format as bullet points suitable for both verbal discussion and printed
take-home sheet. Plain language throughout.
Note: I will verify current prescribing information before using.

9. Medical Uncertainty Communication

prompt
Help me communicate medical uncertainty to a patient — a situation where we
don't yet have a definitive diagnosis or the outcome is uncertain.

Clinical situation: [general description — de-identified]
What is known: [facts available]
What remains uncertain: [what isn't yet known]
Next steps: [planned workup or watchful waiting]
Timeline: [when we'll know more, or what would trigger different action]

Draft patient communication that:
- Acknowledges uncertainty honestly without causing unnecessary fear
- Explains what is known and what is being done
- Gives clear guidance on what to watch for and when to seek care
- Validates the anxiety that uncertainty creates
- Maintains patient confidence in the care plan despite uncertainty

Tone: Honest, calm, empathetic — uncertainty is okay to name
without it feeling like abandonment.

10. Discharge Instructions

prompt
Create discharge instructions for a patient being discharged after:
[condition/procedure — de-identified].

Include:
1. Activity restrictions (specific, not vague)
2. Dietary instructions (if applicable)
3. Wound care (if applicable)
4. Medication instructions (placeholder for specific Rx)
5. Follow-up appointments needed and timeline
6. What to expect in recovery (specific timeline and milestones)
7. Warning signs requiring emergency care (RED FLAGS — prominent)
8. Warning signs requiring urgent clinic call (YELLOW FLAGS)
9. Contact information placeholder

Format: Easy to scan under stress — use headers, bullets, clear hierarchy.
Most important information (follow-up, red flags) should be most prominent.
Reading level: 6th-8th grade.

AI Use in Medicine — Best Practices

Do Use AI For

  • First drafts of written communications
  • Organizing clinical thinking (not replacing it)
  • Patient education material creation
  • Administrative document drafts
  • Learning and research summaries

Never Use AI For

  • Making clinical decisions
  • Processing any identifying patient information
  • As a substitute for clinical examination
  • Replacing specialist consultation
  • Creating documentation without physician review

Privacy and Compliance

  • De-identify all patient information before any AI input
  • Use only institution-approved AI tools where available
  • Follow HIPAA guidelines for any clinical AI use
  • Apply your institution's specific policies

Related Resources

Conclusion

The physicians getting the most from AI are using it where AI is genuinely strong: drafting structured communications, organizing frameworks, and accelerating documentation tasks that don't require clinical judgment. These 10 templates cover the highest-value applications — patient education, documentation structure, and professional communication.

Start with the patient education template (Template 1) for immediate value — translating medical information into accessible language is time-consuming and AI does it well when properly prompted.

newsletter.sh

# Enjoyed this article? Get more in your inbox

Weekly ChatGPT prompt roundups, prompt engineering tips, and AI guides — delivered free. Unsubscribe any time.

$ No spam · Unsubscribe any time · Free forever

Share:
# End of article